Wilson's disease in one identical twin and treatment by triethylene tetramine 2HCl in another case.

WILSON'S disease is a rare genetic condition associated with excess copper deposition in the tissues, principally liver and brain. It first became established as a clinical entity in 1912, following Kinnear Wilson's publication of thirteen cases.' The incidence has been estimated to be about one case per million of the population2 although Walshe3 considers it is likely to be more common than this. Since it is a condition which can be effectively treated, early diagnosis is essential.3 4 In the space of six months, two cases with contrasting features have presented to the Department of Neurology.